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The dGEMRIC Index was 14.4% lower in the medial index compartment (374 61 ms, mean SD) than in the lateral reference compartment (437 59 ms, mean SD) (P<0.001). The dGEMRIC Index of the medial diseased compartment correlated positively with both knee ﬂexor (r¼0.50, P¼0.001) and knee extensor

Objective To determine the association between changes in the delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) index over 2 years as a measure of cartilage proteoglycan concentration, with changes in cartilage thickness in the medial tibiofemoral compartment of knees in middle-aged women. Methods One hundred and forty-eight women (one knee for each subject) aged ≥40 years were included The dGEMRIC was performed as a T1 mapping based on 3-dimensional gradient-echo (3D-GRE) sequence with differ-ent ﬂ ip angle combinations compared to standard IR sequence at 1.5T. We used a Siemens Avanto MRI machine (Siemens Patients who underwent knee arthroscopy in 1999 n = 993 Patients with FCD in one femoral condyle who underwent cartilage dGEMRIC index was calculated by averaging the T1 val-ues in the corresponding 16 central slices (0.9 mm thick). Second, for each of the 4 central thick slices (4 mm thick-ness), the corresponding high resolution dGEMRIC index was calculated from the corresponding 4 thin slices (0.9 mm thickness) and compared. All image analyses were 17 patients with active PsA were evaluated by high-resolution clinical standard morphological and dGEMRIC sequences using a 3T MRI scanner (Magnetom Skyra, Siemens) and a dedicated 16-channel hand coil.

MR imaging protocol Siemens Magnetom Trio 3.0 Tesla (T) magnets (Siemens AG, Erlangen, Germany) were used at three of the seven study sites, two sites used Signa Excite/Genesis 3.0 T … Interestingly, when we compared results from our previously published article assessing the one year effect after intra-articular injection of autologous microfragmented adipose tissue, where out of 331 dGEMRIC measurements, 175 measurements (82.6%) were showing changes with a greater magnitude than 15%, while the remaining 37 dGEMRIC measurements (17.5%) were showing relevant decrease, it Objective: To prospectively compare chemical-exchange saturation-transfer (CEST) with delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) and T2 mapping to assess the biochemical cartilage properties of the knee. Method: Sixty-nine subjects were prospectively included (median age, 42 years; male/female = 32/37) in three cohorts: 10 healthy volunteers, 40 patients with clinically suspected This definition approximates grade 2 knee OA based on the Kellgren and Lawrence scale 36 . MRISubjects were investigated with dGEMRIC 20.6 years (mean; range 18e23) after the injury, using a standard 1.5 T MRI system with a dedicated knee coil (Magnetom Vision; Siemens Medical Solutions, Erlangen, Germany). MRI with dGEMRIC was more sensitive than morphological MRI, and lower dGEMRIC values were found for clock positions with impingement as detected on 3D-CT. This could aid in patient-specific diagnosis of FAI, preoperative patient selection, and surgical decision making to identify patients with cartilage damage who are at risk for inferior outcomes after hip arthroscopy.

Methods: The right knee in 12 asymptomatic volunteers was examined using a 3D Look-Locker sequence on two occasions after an intravenous injection of a double or triple dose of Gd-DTPA2-(0.2 or 0.3 mmol/kg body weight). The relaxation time (T 1) and relaxation rate (R 1 =1/T sequences using a 3T MRI scanner (Magnetom Skyra, Siemens) and a dedicated 16-channel hand coil.

All MR imaging was performed on a 3T MR scanner (MAGNETOM Skyra, Siemens Healthcare, Erlangen, Germany) with a 15-channel Tx/Rx knee coil. Axial and sagittal PD-weighted images with fat saturation, and T1-weighted 3D VIBE images were acquired for morphological analysis.

Here is a table of the equivalent manufacturers' acronyms with the corresponding type of sequence. Type of sequence, Philips, Siemens, GE, Hitachi, Toshiba. evaluated using MRI T2 mapping and dGEMRIC before cartilage treatment was initiated. Inclusion The MRI imaging was performed using a 1.5 T Siemens.

dGEMRIC was performed on a 1.5T Siemens Symphony magnet . Each subject recieved 0.2 mmol/kg of Gd(DTPA) 2 (Magnevist®, Bayer Healthcare) contrast agent, followed by a saline flush. Immediately after contrast administration , each subject walked for 10 minutes to promote diffusion of the contrast into synovial fluid and cartilage.

Second, for each of the 4 central thick slices (4 mm thick-ness), the corresponding high resolution dGEMRIC index was calculated from the corresponding 4 thin slices (0.9 mm thickness) and compared. All image analyses were 17 patients with active PsA were evaluated by high-resolution clinical standard morphological and dGEMRIC sequences using a 3T MRI scanner (Magnetom Skyra, Siemens) and a dedicated 16-channel hand coil. Images were analyzed by two independent raters for dGEMRIC indices, PsA MRI scores (PsAMRIS), and total cartilage thickness (TCT). Background: Even though cartilage loss is a known feature of psoriatic arthritis (PsA), little is known about its role in the pathogenesis of PsA. Using delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) as a non-invasive marker of the tissue's proteoglycan content, such early (i.e., pre-morphological) changes have been associated with inflammation in rheumatoid dGEMRIC All patients were investigated in a standard 1.5 T MRI system (MAGNETOM Avanto, Siemens AG, Erlangen, Germany) with two ﬂexibleBody Matrixcoils positioneddirectlyoverthehips. Patients received 0.2 mg/kg Gd(DTPA)2 (Magnevist®, Schering AG, Berlin, Germany) intravenously, followed by a 10 min timed walk. 2020-05-29 · Even though cartilage loss is a known feature of psoriatic arthritis (PsA), little is known about its role in the pathogenesis of PsA. Using delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) as a non-invasive marker of the tissue’s proteoglycan content, such early (i.e., pre-morphological) changes have been associated with inflammation in rheumatoid arthritis (RA). dGEMRIC was performed on a 1.5T Siemens Symphony magnet .

EVALUATION METHODSThe evaluation included dGEMRIC, isokinetic tests of muscle strength, a functional performance test and calculation of BMI. dGEMRIC A 1.5 T MRI system (Magnetom Vision; Siemens Medical Systems, Erlangen, Germany) with a dedicated knee coil was used for the examinations as previously described 12,20 . Using dGEMRIC, several studies have shown a strong correlation of local joint in-ﬂammation and early cartilage alterations in RA [24,25].
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MRI protocol.

Jul 19, 2020 cartilage (dGEMRIC) index over 2 years as a measure of cartilage Siemens Magnetom Trio 3.0 Tesla (T) magnets (Siemens AG,. Erlangen Oct 22, 2013 Knee cartilage assessment with MRI (dGEMRIC) and subjective knee with a dedicated knee coil (Magnetom Vision; Siemens Medical. Sep 1, 2020 Development of functional MRI sequences like dGEMRIC (delayed mapping sequence (syngo MapIT, Siemens Healthineers, Erlangen, dysplasia, dGEMRIC has been shown to correlate with patient symptoms and performed on the same 1.5T scanner (Magnetom Avanto, Siemens Erlangen).
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Comparison of delayed Gadolinium Enhanced MRI of Cartilage (dGEMRIC) using Inversion Recovery and Fast T1 Mapping Sequences T. C. Mamisch1, M. Dudda2, T. Hughes3, D. Burstein4, and Y-J. Kim 5 1Orthopaedic Surgery, University of Bern, Bern, Switzerland, 2Orthopaedic Surgery, Children's Hospital-Boston, Boston, MA, United States, 3Siemens Medical System,

Of these techniques, only dGEMRIC has so far become clinically use-ful in cartilage repair imaging. a) Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC*) GAG are important to the cartilage tissue’s The dGEMRIC Index was 14.4% lower in the medial index compartment (374 61 ms, mean SD) than in the lateral reference compartment (437 59 ms, mean SD) (P<0.001). The dGEMRIC Index of the medial diseased compartment correlated positively with both knee ﬂexor (r¼0.50, P¼0.001) and knee extensor Interestingly, when we compared results from our previously published article assessing the one year effect after intra-articular injection of autologous microfragmented adipose tissue, where out of 331 dGEMRIC measurements, 175 measurements (82.6%) were showing changes with a greater magnitude than 15%, while the remaining 37 dGEMRIC measurements (17.5%) were showing relevant decrease, it Methods: Twenty-seven participants (age = 28.8 ± 8.6 yrs; BMI = 24.2 ± 2.3 kg m −2; 44% females) diagnosed with FAI syndrome (cam-, pincer- or combined-type FAI morphology concurrent with symptoms) underwent hip MRI with delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) in one of two 3T scanners (Siemens Prisma, Siemens Skyra). The using 3D dGEMRIC at two different doses of the contrast agent Gd-DTPA2-. Methods: The right knee in 12 asymptomatic volunteers was examined using a 3D Look-Locker sequence on two occasions after an intravenous injection of a double or triple dose of Gd-DTPA2-(0.2 or 0.3 mmol/kg body weight).